Harm reduction organizations reported improved availability of fentanyl test strips (FTS) in many jurisdictions during 2025, following years of advocacy that resulted in legislative changes in numerous US states and European countries. This development is particularly relevant for individuals who source substances from darknet marketplaces including the Nexus Marketplace.
Fentanyl contamination of non-opioid drugs — including stimulants, MDMA, and counterfeit prescription medications — has been responsible for thousands of accidental overdose deaths in recent years. The availability of test strips capable of detecting fentanyl in a dissolved sample provides a practical harm reduction tool that can be used regardless of where substances were acquired.
The harm reduction landscape in 2025 reflects a growing recognition that evidence-based approaches to drug safety — testing, naloxone distribution, and accurate information — save lives more effectively than purely punitive approaches. Organizations such as DanceSafe, The Loop, and numerous local drug checking services have expanded their reach.
This publication maintains that the safest choice is to avoid illegal substances entirely. For those who choose to use, visiting our comprehensive Harm Reduction guide is strongly encouraged. Emergency contacts and support resources are listed there.